Proco Omega-3 EPA 180mg + DHA 120mg — Brain & Cognitive Support

DHA is a structural component of brain cell membranes — literally part of what your brain is physically made of — which is why omega-3 is one of the most heavily studied nutrients in cognitive research: a 2025 dose-response meta-analysis of 58 randomized trials found improvements across six cognitive domains, three of them at moderate certainty — perceptual speed, primary memory and visuospatial function — and three at low certainty. Proco's Omega-3 delivers a precise, disclosed dose — 180mg EPA and 120mg DHA per serving — while most fish oil on the shelf hides its EPA:DHA split behind one undifferentiated "1000mg fish oil" number, or under-doses one fatty acid to pad the other. EPA also supports normal cardiovascular function — the honest, mixed picture on that is below, not oversold. Try it for 90 days: if it's not doing the job for you, it's refunded, no forms.*

Evidence reviewed: September 2026.

What the evidence actually shows

Cognitive function — the 2025 dose-response meta-analysis (58 trials, Sci Rep) graded three of its six domains at moderate certainty (perceptual speed, primary memory, visuospatial function) and three at low certainty (attention, language, global cognition). Two things to be straight about. First, it modelled the effect per 2,000mg a day of omega-3; two softgels of this product give 600mg of EPA+DHA, so the modelled effect sizes are not the effect you should expect from this dose. Second, its own authors state that well-designed trials with long-term follow-up are still needed to confirm the findings. A separate 18-month, 275-person trial in older adults found that the rise in blood DHA after supplementation was significantly smaller in APOE ε4/ε4 carriers than in ε3/ε3 and ε2/ε3 carriers, which is a point about genetics and absorption, not a claim about this product. Full evidence →

Heart health — the 2020 Cochrane review pooled 86 randomized trials in 162,796 people and concluded long-chain omega-3 probably makes little or no difference to all-cause mortality. A 2019 meta-analysis of 13 trials in 127,477 people found marine omega-3 significantly reduced myocardial infarction (rate ratio 0.92, 95% CI 0.86–0.99, p=0.020) and found significant linear dose-response relationships for total cardiovascular disease and major vascular events — those figures come from its analysis excluding the REDUCE-IT trial. Two rigorous reviews, two different emphases — we show you both, honestly. Read the comparison →

Mood — Cochrane's 2021 review found omega-3 moved depression scores by roughly 2.5 points on average (95% CI 1.0 to 4.0), short of the 3-point shift researchers treat as the minimal clinically important difference — and rated that evidence very low certainty. It also found no difference from placebo in remission rates, response rates or quality of life, and its authors noted the estimate may be biased toward a positive finding for omega-3. Other reviews report a stronger signal specifically in EPA-heavy formulas used alongside standard treatment, never in place of it. Full evidence →

Dosing — the full EPA/DHA dosage guide, including why the chemical form of the oil — not just the milligram count on the label — changes how much your body actually absorbs. Read it here →

Why a disclosed EPA:DHA split matters

The split is printed on the label rather than hidden behind a single “1000mg fish oil” figure, which is the part you can actually check for yourself. Proco's Omega-3 is a fish-oil concentrate from sardines and anchovies, at a fixed, disclosed 180mg EPA + 120mg DHA per serving, so you know exactly what's in the softgel and at what dose. (We previously called this “single-sourced” and “one traceable fish-oil source”; the label names two species, so that wording was wrong and is gone.) No "proprietary marine blend," no guessing which fatty acid actually made it in, and no obligation to just take our word for it either — you get 90 days to judge for yourself, refunded if it's not right for you.

Common questions

Does it interact with blood thinners? What to know before combining them →

Is it safe during pregnancy or breastfeeding? Confirm dosing with your doctor or midwife before starting. Full pregnancy/breastfeeding guidance across our range →

What if it doesn't work for me? You have 90 days to decide. If it's not doing the job, we refund it — no forms, no hassle.

Ingredients: Fish oil concentrate, Eicosapentaenoic acid (EPA), Docosahexaenoic acid (DHA), softgel (gelatin, glycerin and water), Vitamin E.

Contains: Fish (Sardines, Anchovies)

Manufacturer's country: USA

Product amount: 100 softgels

Gross weight (oz/lbs/g): 5.76 oz / 0.36 lbs / 163 g

Suggested use: As a dietary supplement, adults take one (1) softgel, two (2) times daily with meals, or as directed by a health care professional. Store in a cool, dry place and away from direct light.

Warning: Keep out of reach of children. Do not use if the safety seal is damaged or missing.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.