Plain-language explainers on ADHD, autism, sleep, memory and more. Each one sets out what the evidence says and where it stops.
General information only, not medical advice. We are not a clinical service yet.
More people take hormonal contraception than take any drug in the four medication classes we have already written about, and the question of what it does to mood has…
Antipsychotics are the hardest medication class to write about honestly, because the gap between what they are licensed for and what they are actually prescribed for is…
Stimulants are the most effective treatment in psychiatry by effect size, and the most argued about.
If you are currently taking a benzodiazepine, do not stop or reduce it based on anything in this article.
If you are in crisis, stop reading and get help now. Samaritans, free from any phone in Ireland and the UK: 116 123 , 24 hours, every day.
A tub of melatonin gummies costs about the same as a bottle of Sleep Formula, tastes considerably better, and is on the shelf of every pharmacy.
You are standing in a pharmacy at nine in the evening. On one shelf is a packet of antihistamine sleeping tablets — diphenhydramine or doxylamine, sold under names like…
This is one of the most common questions people ask before buying a melatonin product.
Physical inactivity is the last of the Lancet Commission's fourteen modifiable dementia risk factors to get its own post here, and the one where we have least to gain…
Most of the fourteen modifiable dementia risk factors the Lancet Commission names are things a person can act on or a clinician can treat — blood pressure, hearing…
Two of the fourteen modifiable risk factors on the Lancet Commission's list were added in the 2024 update: raised LDL cholesterol in midlife, and untreated vision loss…
You already know smoking is bad for you. The questions worth answering are narrower: what does quitting give back, on what timescale, and is there an age at which it…
Of the fourteen modifiable dementia risk factors the Lancet Commission names, raised LDL cholesterol is the odd one out: most adults over forty have already had it…
How insulin resistance and type 2 diabetes damage the brain across decades, and why the trials that lowered blood glucose did not improve cognition, is covered in full…
We sell nothing for tinnitus and would not. That is exactly why it is worth writing about properly: there is nothing at the end of this article to buy, which makes it…
Two of our articles name medication as a cause of cognitive fog and move on. What actually causes brain fog lists it among several causes; the blood-test piece calls it…
Cognitive reserve is the idea that two people can carry the same disease burden in their brains and only one will look ill.
We have cited the Lancet Commission's list of modifiable dementia risk factors repeatedly without ever writing about the item on it that is easiest to find and easiest…
First, what this article is not about. If you are here because you feel foggy and flat at three in the afternoon, that is a different subject and we have written it up…
Social isolation is one of the fourteen modifiable risk factors on the Lancet Commission's list.
Two specific learning differences that are common, frequently undiagnosed in adults, and surrounded by more myth than almost anything else in this area.
An autistic adult who has been coping for years hits a wall. The exhaustion does not lift with a weekend.
If you're in crisis right now, this page is the wrong place. In Ireland and the UK, Samaritans is 116 123 — free, 24 hours.
Two things about tics are almost universally misunderstood, and both change how you'd respond to them.